4-[(7-oxo-7H-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-N-pyridin-2-yl-benzenesulfonamide

This compound is a synthetic small molecule belonging to the class of aminobenzenesulfonamides. It features a thiazolo-indole core structure linked via a methylamine bridge to a pyridine-substituted benzenesulfonamide. The molecule has been studied as an experimental agent and is not approved for clinical use. Its primary mechanism of action is as an inhibitor of cyclin-dependent kinase 2 (CDK2), which plays a key role in cell cycle regulation and proliferation. Inhibition of CDK2 can induce cell cycle arrest and apoptosis in cancer cells; thus this compound has been investigated for potential anticancer activity. No marketed products or advanced clinical development are reported for this agent.

Other names

4-[({7-oxo-[1,3]thiazolo[5,4-e]indol-8-yl}methyl)amino]-N-(pyridin-2-yl)benzenesulfonamide4-{[(7-Oxo-[1,3]thiazolo[5,4-e]indol–8–yl)methyl]amino}-N-(2-pyridinyl)benzenesulfonamideBenzenesulfonamide, 4-[[(7–oxo–7H-thiazolo[5,4-e]indol–8–yl)methyl]amino]-N-(pyridin–2–yl)